Intrauterine insemination (IUI) is an insemination technique, which involves the insemination of a prepared sperm sample directly into the uterine cavity at the time of ovulation. IUI can be performed in a natural (unstimulated) cycle or a stimulated cycle with fertility drugs. IUI can sometimes give higher pregnancy rates when combined with ovarian stimulation. The use of fertility drugs can be advantageous because they stimulate the ovaries to produce more than one egg each cycle, which can increase the chance of pregnancy.
“IUI can be performed in a natural (unstimulated) cycle
or a stimulated cycle with fertility drugs.”
However, ovarian stimulation increases the chance of multiple pregnancies, which is why regular ultrasound scans are necessary to identify the number of follicles developing in the ovary. The treatment cycle is abandoned if there is no follicle development or if more than three follicles are developing. Once the follicle is big enough and the lining of the uterus is suitably thickened, an injection of HCG will be given to trigger ovulation.
The male partner is asked to produce a semen sample in the same day of IUI. We advise sexual abstinence for 2-3 days before the collection. After sperm preparation, a portion of sperm will be placed into the uterus by a fine catheter. IUI with prepared sperm is recommended for couples with non-obstructed fallopian tubes.